NIOSHTIC-2 Publications Search

Methyl Ethyl Ketone Peroxide Potential Occupational Hazards.

Authors
Anonymous
Source
NIOSH 1977 Oct:37-41
NIOSHTIC No.
00075410
Abstract
This information profile on methyl-ethyl-ketone-peroxide (1338234) lists its molecular structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures and economic trends in production, uses, number of companies producing and using the substance, and the biological effects of exposure. Given orally, by inhalation, or by intraperitoneal injection, methyl-ethyl-ketone-peroxide causes hyperemia of the lungs with petechial or gross hemorrhage in mice and rats. Liver damage has been associated with subacute exposures. The compound also irritates eyes and skin. Acute, subchronic, and chronic effects of exposure are discussed. In humans chemical burns of the gastrointestinal tract, as well as residual scarring and structure of the esophagus were noted in an individual surviving ingestion of two ounces of a 60 percent solution. The threshold limit value is set at 0.2 ppm. (Contract No. 210-77-0120)
Keywords
NIOSH-Contract; Contract-210-77-0120; Toxic-substances; Thresholds; Peroxides; Gastrointestinal-system-disorders; Plastics-industry; Synthetic-resins; Composites; Respiratory-system-disorders; Liver-disorders; Irritants;
CAS No.
1338-23-4;
Publication Date
19771001
Funding Type
Contract;
Fiscal Year
1978
Identifying No.
Contract-210-77-0120
Priority Area
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders;
Source Name
Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division