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NIOSH 1977 Oct:12-15
This information profile on furfuryl-alcohol (98000) lists its chemical structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures and economic trends in production, uses, number of companies producing and using the substance, and the biological effects of exposure. Furfuryl-alcohol mainly affects the central nervous system, causing death by respiratory depression. It displays antispasmodic effects on smooth muscles while causing paralysis of sensory nerves and, in rabbits, paralysis of skeletal muscles. Pulmonary damage has also been observed. Acute, subacute and chronic effects are discussed. A study of ten iron and steel foundries is cited where 22% of the measurements for furfuryl-alcohol concentrations in the air of coremaking areas exceeded the acceptable threshold limit value of 5.0 ppm. Small doses of furfuryl-alcohol stimulate human respiration, but larger doses depress respiration, reduce body temperature, produce nausea, salivation, diarrhea, dizziness, and diuresis.
NIOSH-Contract; Contract-210-77-0120; Nervous-system-disorders; Chemical-industry; Respiratory-system-disorders; Mortality; Thresholds; Resins; Alcohols; Musculoskeletal-system-disorders; Gastrointestinal-system-disorders;
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders; Musculoskeletal-system-disorders;
Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977
Page last reviewed: September 2, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division