This information profile on benzyl-chloride (100447) lists its chemical structure, Chemical Abstracts Service number, Registry of Toxic Effects of Chemical Substances number, production figures and economic trends in production, uses, number of companies producing and using the compound, along with information regarding its biological effects. Benzyl-chloride is highly irritating to eyes, ears, nose, and throat and can cause lung edema. Dermal applications show that it is a strong sensitizing agent. Reports of leukopenia from exposure are noted. Acute, subchronic, and chronic effects are detailed with specific attention given to mutagenicity, carcinogenicity and teratogenicity. Human exposure to benzyl- chloride at 16 ppm for one minute is intolerable. The threshold limit value is 1 ppm. Other standards for this substance are briefly mentioned.
Information Profiles on Potential Occupational Hazards, NIOSH Contract No. 210-77-0120, October 1977