Ocular effects of ultraviolet radiation from 295 to 365 nm.
Pitts DG; Cullen AP; Hacker PD
Investig Ophthalmol Vis Sci 1977 Oct; 16(10):932-939
A 5,000 watt xenon mercury source and a double monochromator were used to produce 6.6 nanometer full band-pass ultraviolet (UV) radiation. Pigmented rabbit eyes were exposed to the 6.6 nanometer band pass UV radiant energy in 5 nanometer steps from 295 to 320 nanometer and at random intervals above 320 nanometer. Corneal and lenticular damage was assessed and classified with a biomicroscope. Corneal threshold radiant exposure rose very rapidly from 0.022 Joules per square centimeter at 300 nanometers to 10.99 Joules per square centimeter at 335 nanometers. Radiant exposures exceeding two times the corneal threshold radiant exposure resulted in irreversible corneal damage. Lenticular damage was limited to wavebands above 295 nanometers. The action spectrum for the lens began at 295 nanometers and extended to about 315 nanometers. Permanent lenticular damage occurred at radiant exposure levels approximately twice the threshold for lenticular radiant exposure. The importance in establishing both corneal and lenticular damage criteria is emphasized. (Contract No. 099-74-0012)
NIOSH-Publication; NIOSH-Contract; Contract-099-74-0012; Nonionizing-radiation; Eye-disorders; Thresholds; Ultraviolet-light; Cornea-disorders; Exposure-limits; Physical-properties; Dosage; Threshold-limit-values;
Author Keywords: ultraviolet radiation; corneal damage; lenticular damage; cataract; action spectrum; anterior uveitis; rabbits; biomicroscopy; ultraviolet thresholds
Investigative Ophthalmology and Visual Science
University of Houston College of Optometry,