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Ciliary inhibition and axonemal microtubule alterations in freshwater mussels.
Adshead PC; Martinez JR; Kilburn KH; Hess RA
Ann NY Acad Sci 1975 Jun; 253:192-212
This study was designed to examine ciliary structure during the different stages of ciliary inhibition in freshwater mussels. Rapid microtubular disappearance occurs in the terminal cilia of the freshwater mussel Unio when exposed to cystic fibrosis (CF) serum causing a shock stop reaction. Return to water allows resumption of normal ciliary beating. In contrast, a slow stop reaction causes distortion of cilia, asynchronous beating, and ejection of cells from the distal gill filament, but ciliary axonemal structure is preserved. Slow stopped cilia do not resume their beating in water. Saliva from reserpine treated rats causes ciliary inhibition similar to that induced by CF serum.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Pancreatic-cystic-fibrosis; Cilia; Hair; Nervous-system; Physiological-response
Medicine University of Missouri N424 Medical Center Columbia, MO 65201
Annals of the New York Academy of Sciences
University of Missouri Columbia, Columbia, Missouri
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