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Chromosome damage by chemical agents in humans.

Authors
Forni A
Source
NIOSH 1974 Jan; :2-7
Link
NIOSHTIC No.
00071226
Abstract
The chromosomal effects of chemicals in man may be studied by in- vivo or in-vitro methods. In vivo testing detects damage which has already occurred, while in vitro testing can be used to screen suspect chemicals and determine cytotoxicity levels. Chemicals which are known to cause chromosome damage include drugs, alkylating agents, solvents, inorganic chemicals, pesticides, food additives, and air and water pollutants. Exposure to these substances may result from use or occupational or environmental exposure. The medical implications of this damage are not known, and there are likely to be changes which are invisible and must be detected by other means. There is a great range in susceptibility to chromosome damage among individuals. (Grant No. R01-OH-00339)
Keywords
NIOSH-Grant; Grants-other; Toxic-substances; Air-pollution; Screening-tests; Environmental-contamination; Measurement-methods; Genetics; Toxicity; Alkyls; Occupations; Detection; Tolerance
Contact
None Via S Barnaba, 8 20122 Milan, Italy 20122 Milano, Italy
Publication Date
19740101
Document Type
Conference/Symposia Proceedings
Funding Amount
25500
Funding Type
Grant
Fiscal Year
1974
Identifying No.
Grant-Number-R01-OH-00339
Priority Area
Other Occupational Concerns; Grants-other
Source Name
Proceedings of the Second International Symposium on Chromosome Aberrations by Industrial Chemicals and Vinyl Chloride Toxicity, Milan, Italy, October 28-29, 1974, NIOSH Grant No. R01-OH-00399
Performing Organization
University of Milan, Milan, Italy
Page last reviewed: May 11, 2023
Content source: National Institute for Occupational Safety and Health Education and Information Division