HHE Determination Report No. HHE-75-THIRAM-352, Composite Report on Thiram.
NIOSH 1976 Dec:64 pages
A health hazard evaluation conducted by NIOSH determined that Thiram poses a toxic hazard to both nursery workers and tree planters in the reforestation industry (SIC-8021, SIC-0851) in the Pacific Northwest. Environmental sampling yielded non-toxic air levels of Thiram (137268), but demonstrated a considerable variation in the amount of Thiram to be found on the trees to which the workers were exposed. Skin irritation in a portion of the work force due to direct contact with Thiram treated trees was suggested by symptoms reported during the few days each individual group was studied, in addition to being identified in the general medical histories. Irritation of eyes, nose and throat caused by Thiram exposure was identified by general medical history. However, during the individual periods of study the incidence of these symptoms occurring during the study period failed to show significant differences between groups working with Thiram and groups not working with Thiram. Systemic symptoms were attributed to exposure to Thiram by history, particularly when exposed to heavily sprayed trees or when the work week was extended beyond five days. These symptoms include headache, dizziness, nausea, diarrhea and other stomach complaints, fatigue and an intolerance to alcohol. It is of note that the alcohol intolerance described by history was generally fairly mild as compared to that experienced by persons taking the drug disulfiram (97778).
NIOSH-Publication; NIOSH-Author; HHE-75-THIRAM-352; Region-10; Hazard-Confirmed; Air-quality-measurement; Air-contamination; Toxic-chemicals; Exposure-limits; Skin-irritants; Agricultural-chemicals; Skin-disorders; Statistical-analysis; Gastrointestinal-system-disorders; Respiratory-irritation; Eye-irritation; Toxicology; Fungicides;
Hazard Evaluation and Technical Assistance; Field Studies
NTIS Accession No.
Hazard Evaluation Services Branch, NIOSH, Cincinnati, Ohio, Report No. HHE-75-THIRAM-352, 64 pages, 10 references