The teratogenic effect of an organophosphorated insecticide (parathion) in the bird embryo.
Archives, d'Anatomie, d'Histologie et d'Embryologie 1973 Jan; 56(1):97-110
Parathion administered before incubation, or at the first stages of incubation, is found to give to chicks and Japanese quail serious axial deformities. The cervical part of the rachis is the most strongly distorted and shows scoliosis, cyphosis, and lordosis. Histological studies reveal that the vertebral centers join together as do the neural arches. Craniovertebral joint is also very deteriorated by ventral anastomoses of the vertebrae. Parathion administered to embryos at different stages of incubation gives also serious morphological abnormalities of the cervical region of the vertebral column. (French; English translation available)
AAHEAF; Organophosphorus-compounds; Organophosphorus-insecticides; Pesticides; Teratogens; Mutagens; Toxic-substances; Teratogenesis; Reproductive-system-disorders; Morphology; Anticholinergens; Skeletal-disorders
Archives, d'Anatomie, d'Histologie et d'Embryologie