Respiratory response to tobacco dust exposure.
Valic-F; Beritic-D; Butkovic-D
Am Rev Respir Dis 1976 Jun; 113(6):751-755
Results of a study of the respiratory responses of 318 nonsmoking female workers to long-term tobacco dust exposure are reported. The mean total tobacco dust concentrations range from 0.9 to 27.5 milligrams per cubic meter; the respirable fraction, from 0.3 to 3.6 milligram per cubic meter. The mean length of exposure to tobacco dust is 14.9 years, 24 percent of workers having been exposed to tobacco dust for 20 years or more. Comparatively low prevalences of chronic respiratory symptoms are found, and only the prevalences of chest tightness and wheezing are significantly higher among workers exposed to tobacco dust than those of the control group. In contrast to negative findings with regard to chronic respiratory effects, significant acute decreases in ventilatory capacity during the work shift are recorded. No dose-response relationship is found between the level of exposure and the acute decreases in ventilatory capacity.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Toxic-substances; Dust-control; Organic-dusts; Lung-disorders; Chest-disorders; Respiratory-system-disorders; Chronic-diseases; Tobacco-industry; Lung-ventilation; Respiratory-functions
American Review of Respiratory Disease