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Occupational health and safety symposia. Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 76-136, 1976 Feb; :209-219
The physical characteristics of particle size, diffusion, deposition and retention that affect the physiology and pathology of occupational pneumoconioses in human workers exposed to hazardous dusts are outlined. Mechanisms in the deposition of particulate matter in the respiratory tract include gravitational settling, diffusion or Brownian motion and inertial impaction. The pneumoconioses discussed include silicosis, asbestosis, byssinosis, bagassosis and berylliosis, and other dust-caused diseases discussed include systemic reaction, metal fume fever, irritation of the nose and throat, allergic reactions, radioactive damage and carcinogenic damage. The concepts of threshold limit value and dose response relationships are defined.
NIOSH-Author; NIOSH-Contract; Contract-210-75-0033; Airborne-particles; Airborne-particulates; Cancer; Physical-properties; Respiratory-system-disorders; Lung-fibrosis; Lung-disorders; Dosage; Physiological-mechanisms; Exposure-limits; Radiation
Occupational health and safety symposia
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division