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Carcinogenicity of arsenic experimental studies.

Authors
Kraybill-H
Source
Health effects of occupational lead and arsenic exposure, a symposium, Carnow BW, ed. Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 76-134, 1976 Feb; :272-278
Link
NIOSHTIC No.
00056240
Abstract
Experimental work on arsenic (7440382) and arsenic compounds covers a wide range of doses, with concentrations as low as 0.0004 ppm of the compound in solution to as high a level as 646 ppm in diet given to rodents. Skin absorption studies (skin painting) with mice also reflect a dose range from a low level of 0.4 percent to a high level of 1.8 percent. All of the studies were essentially negative insofar as neoplastic lesions were concerned. There were a few studies in mice which indicated some tumors, adenocarcinomas of the skin, lung, and lymph nodes, but these studies are difficult to interpret on the basis of inadequacy in the design.
Keywords
NIOSH-Author; NIOSH-Contract; Contract-210-75-0026; Toxicology; Metal-poisoning; Heavy-metals; Arsenic-poisoning; Percutaneous-absorption; Skin-tests; Skin-penetration; Carcinogenesis; Skin-cancer; Lung-cancer; Lymphatic-cancer; Histopathology
CAS No.
7440-38-2
Publication Date
19760201
Document Type
Conference/Symposia Proceedings
Fiscal Year
1976
NTIS Accession No.
NTIS Price
NIOSH Division
DSHEFS
Source Name
Health effects of occupational lead and arsenic exposure, a symposium.
State
IL; OH
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