Biological Monitoring Problems of Blood Lead Levels.
NIOSH 1976 Feb:27-37
Blood lead (7439921) levels pose problems that involve ethical, technical, toxicological, and societal considerations. Workers may legitimately object to periodic blood sampling to monitor their work environments, and technical problems and inherent errors associated with procedures reduce the accuracy of blood samples in evaluating toxic potential for workers. The inadequacy of blood lead for measurement of occupational exposures was demonstrated in a small population of lead workers in which those with blood lead concentrations below 80 micrograms per 100 milliliters of blood were found to have unequivocal biochemical effects when a more sensitive testing method was used. The coexistence of such abnormalities with acceptable blood lead levels casts doubts on the value of the entire blood lead measurement as a reliable index of hazardous exposure to and absorption of lead.
NIOSH-Author; NIOSH-Contract; Contract-210-75-0026; Toxicology; Metal-poisoning; Heavy-metals; Lead-poisoning; Blood-chemistry; Diagnostic-tests; Occupational-health; Microanalysis; Test-methods;
Health Effects of Occupational Lead and Arsenic Exposure, A Symposium; Division of Surveillance, Hazard Evaluation and Field Studies, NIOSH