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Sensory irritation by sulfite aerosols.
Alarie Y; Wakisaka I; Oka S
Environ Physiol Biochem 1973 Aug; 3(4):182-184
Mice were exposed to aerosols of sodium-sulfite (7631905) and sodium- metabisulfite (7681574) and sensory irritation to the upper respiratory tract was measured. Sodium-sulfite was inactive, but sodium-metabisulfite was found to evoke sensory irritation in a fashion comparable to sulfur-dioxide. The findings indicate that sensory irritation is due to the presence of the bisulfite anion formed in the slightly alkaline pH of the nasal mucosa when animals are exposed to sodium-metabisulfite or sulfur-dioxide (7446095).
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Air-contaminants; Respiratory-irritants; Sensory-processes; Gases; Irritants;
Occupational Health University of Pittsburgh 130 DE Soto Street Pittsburgh, PA 15213
7631-90-5; 7681-57-4; 7446-09-5;
Issue of Publication
Environmental Physiology and Biochemistry
University of Pittsburgh, Pittsburgh, Pennsylvania
Page last reviewed: January 14, 2022
Content source: National Institute for Occupational Safety and Health Education and Information Division