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Some Physiological Aspects of Dysbarism-Induced Osteonecrosis.
The pathology of dysbarism-induced osteonecrosis appears to be related to a previous state of ischemia. The evidence for a hypothesis for delayed ischemia based on the hypersensitivity of the mineralization process to local water content. Different concentrations of gases can induce osmosis across sections of articular cartilage and other tissues. These effects are noted during compression and decompression, and when nitrous oxide is substituted for nitrogen. Removal of only 5-10% of water induces spontaneous nucleation of crystals. Rapid pressure changes in either compression or decompression should be avoided to prevent osteonecrosis.
Bone-disorders; Physiology; Pressure-control; Safety-practices; Crystallization; Bone-structure; Workers;
Dysbarism-Related Osteonecrosis, Proceedings, of a Symposium on Dysbaric Osteonecrosis, NIOSH, Cincinnati, Ohio
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division