Interaction of coal dusts with essential metals.
Kettering Laboratory, Department of Environmental Health, College of Medicine, University of Cincinnati 1974 Jan; :1-18
Tests were performed to determine the content of cadmium (7440439), copper (7440508), iron (7439896), nickel (7440020), lead (7439921) and zinc (7440666) in coal dust, and the removal of these metals from the coals using organic and aqueous solvents. The fractions containing organic compounds were removed by leaching the coals with organic as well as aqueous acidic and basic solvents. The organic solvent leached fractions were worked up to obtain the chelating components. These were then purified by removing metal contaminants. The bases and acids contained in these fractions were then demonstrated to have chelating activity. The organic, acid and base soluble components of the above fractions were then used to demonstrate inhibition of the metal dependent enzyme, galactose oxidase. Finally, an attempt was made to determine how much of these materials can be obtained from the two coals under mild and rigorous exhaustive conditions of removal. Since the organic leaching is done at room temperature and under non-hydrolytic conditions this may be the method of choice to remove intact coal components.
NIOSH-Grant; Grants-other; Trace-metals; Trace-analysis; Heavy-metals; Solvent-extraction; Enzyme-activity; Biochemical-reactions; Enzymatic-inhibition; Biochemical-effects; Analytical-methods; Dust-analysis; Microanalysis;
Environmental Health University of Cincinnati Eden & Bethesda Avenues Cincinnati, Ohio 45219
7440-43-9; 7440-50-8; 7439-89-6; 7440-02-0; 7439-92-1; 7440-66-6;
Final Grant Report
Other Occupational Concerns; Grants-other
Kettering Laboratory, Department of Environmental Health, College of Medicine, University of Cincinnati
University of Cincinnati, Cincinnati, Ohio