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HHE determination report no. HHE-73-173-244, Borden Chemical Company, Leominister, Massachusetts.
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HHE 73-173-244, 1975 Dec; :1-12
Some workers exposed to the enzyme trypsin are found to have developed allergic sensitization. Episodic exposure to trypsin (9002077) is found to result in respiratory impairment in those employees who have become sensitized and mild upper respiratory tract irritation among other workers who have not become sensitized. Workers engaged in the handling of the surfactant Nekal B-78 (SIC- 2819) periodically experience upper airway irritation, gagging and shortness of breath: the problem is found to be the result of poor work practices.
NIOSH-Health-Hazard-Evaluation; NIOSH-Author; Hazards-Confirmed; HHE-73-173-244; Region-1; Chemical-manufacturing-industry; Air-contamination; Allergies; Hypersensitivity; Author Keywords: trypsin; allergic sensitization; pulmonary function test; surfactant
Field Studies; Hazard Evaluation and Technical Assistance
NTIS Accession No.
National Institute for Occupational Safety and Health
Page last reviewed: May 5, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division