Effects of environmental pollutants in germfree rodents.
Terminal Progress Report 1974 Dec; :1-3
Tissues from rats exposed to coal dust are examined histopathologically. The lesions are confined to the lungs as clearly-defined granulomas in the parenchyma of the lungs, but not complicated by bacterial agents. Results indicate that the reactions induced in the germfree rats by inhalation of coal and quartz dusts are more clearly defined than by use of conventional animals, and that they would be valuable in quantitative studies on environmental pollutants.
NIOSH-Grant; Pulmonary-system-disorders; Respiratory-system-disorders; Air-contaminants; Coal-mining; Lung-cancer; Bioassays; Dust-control
Lobund Laboratory University of Notre Dame Lobound Laboratory Notre Dame, Ind 46556
Final Grant Report
Terminal Progress Report
University of Notre Dame, Notre Dame, Indiana