Atomic absorption spectrometry of trace metals in clinical pathology.
Hum Pathol 1973 Dec; 4(4):549-582
According to a review of the literature, atomic absorption spectrometry provides a convenient and versatile instrumental method for measurements of trace metals in biological materials. An important innovation is the recent development of nonflame atomization devices, which have substantially improved the analytical sensitivity of atomic absorption spectrometry. Applications of atomic absorption spectrometry of trace metals in clinical pathology have been expanded by the recent recognition of clinical syndromes associated with copper (7440508) and zinc (7440666) deficiency, and the discovery of abnormalities of chromium (7440473) and nickel (7440020) metabolism in various human diseases. Details are given regarding the analysis of lead (7439921) and iron (7439896).
NIOSH-Publication; NIOSH-Contract; Contract-099-72-0024; Analytical-methods; Trace-analysis; Microanalysis; Test-methods; Diagnostic-tests; Metabolic-disorders; Metal-poisoning; Instrumentation
F. William Sunderman, Jr., M.D., Department of Laboratory Medicine, University of Connecticut School of Medicine, P.O. Box G, Farmington, Connecticut 06032
7440-50-8; 7440-66-6; 7440-47-3; 7440-02-0; 7439-92-1; 7439-89-6