Pulmonary Function and X-ray Changes in Granite Dust Exposure.
Theriault GP; Peters JM; Murphy RL; Ashe HB
Department of Physiology, Harvard School of Public Health, Boston, Massachusetts 1973:22 pages
Chest X-rays of 784 granite shed workers were classified according to the UICC/Cincinnati Classification, and their relationships to lifetime dust exposure, ventilatory function, and smoking habits of the workers were studied. Increase in dust exposure correlated with increase in size of rounded opacities (p to q) and from profusion 1 to 2, supporting the progression in size as well as in number of opacities with dust exposure. Irregular opacities were related more to smoking than to dust. Forced vital capacity (FVC) was lower for people with positive X-rays and decreased with higher profusion. No difference in ventilatory capacities between p and q was noted. Residual volume (RV) increased with smoking but not with dust exposure. No trend was shown for total lung capacity (TLC), but its two components RV and FVC varied in opposite directions. A dose response of dust on ventilatory function and on X-ray showed that the effects on ventilatory capacity take place 13.5 years before opacities on X-rays.
NIOSH-Contract; Contract-099-72-0066; Roentgenology; Pulmonary-function; Diagnosis;
Department of Physiology, Harvard School of Public Health, Boston, Massachusetts