Role of relative humidity in the synergistic effect of a sulfur dioxide-aerosol mixture on the lung.
McJilton-C; Frank-NR; Charlson-R
Science 1973 Nov; 182(4111):503-504
Experimental evidence is reported concerning the physicochemical and biological factors involved in the potentiation of the irritant property of sulfur-dioxide (7446095) in combination with an aerosol, in the lungs of the guinea pig. Relative humidity is an important variable for those aerosols capable of absorbing water at relative humidities below 95 percent. The results are in agreement with proposed hypotheses for gas-aerosol synergism.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Interactions; Inorganic-gases; Air-contaminants; Sulfur-oxides; Respiratory-irritants; Toxicology; Time-dose-relationship; Respiratory-system-disorders
Preventive Medicine University of Washington Dept of Preventive Medicine Seattle, Wash 98105
University of Washington, Seattle, Washington