Hyperthyroidism and cortisol secretion in man.
Gallagher-TF; Hellman-L; Finkelstein-J; Yoshida-K; Weitzman-ED; Roffwarg-HD; Fukushima-DK
J Clin Endocrinol Metab 1972 Jun; 34(6):919-927
The pattern of cortisol (50237) secretory activity of 4 patients with severe spontaneous hyperthyroidism was studied by sampling plasma every 20 minutes for 24 hours. The hyperthyroid patients are found to exhibit: more cortisol secretory episodes than normal; more of the 24 hours was spent in adrenal secretory activity; increased production of cortisol in conjunction with a shortened half-life of plasma cortisol; functional adrenal hypertrophy; and retention of the normal about midnight concentration of plasma cortisol at zero or virtually zero for a prolonged time.
NIOSH-Publication; NIOSH-Grant; Grants-other; Blood-chemistry; Endocrine-system-disorders
Division of Neurology Montefiore Hosp and Med Center Division of Neurology Bronx, N Y 10467
Journal of Clinical Endocrinology and Metabolism
Montefiore Hospital and Medical Center, New York, New York