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Effect of intrapulmonary water instillation on pulmonary lymph flow and composition.
Am J Physiol 1972 Dec; 223(6):1433-1437
Intrapulmonary instillation of water in anesthetized, closed-chest, artificially ventilated dogs is followed by an increase in right lymphatic duct lymph flow. The increase is proportional to the amount of water instilled. A significant decrease in lymph sodium concentration without a significant change in lymph protein concentration is observed following the instillation of 10 milliliters per kilogram water. Evans blue concentration ratio is found to be 19, with a steady-state value of 10 at 5 hours. Intrapulmonary water instillation produces a striking decrease in lymph/plasma Evans blue ratio. In addition to water transport, lymphatics play a specific role in high molecular weight solute transport.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Respiratory-system; Lymphatic-system; Lymph-plasma-ratio; Pulmonary-lymphatics; Author Keywords: pulmonary lymphatics; pulmonary lymph flow; Na+ transport; Evans blue transport; pulmonary lymph protein transport
Julio C. Acevedo, Departments cf Medicine and Physiology, Stanfcrd lJniversity School of Medicine, Stanford, California 94305
Issue of Publication
American Journal of Physiology
Stanford University, Stanford, California
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division