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Work activity and coronary heart mortality.
Paffenbarger RS Jr.; Hale WE
N Engl J Med 1975 Mar; 292(11):545-549
A 22 year follow up study is made of longshoremen to appraise the role of physical activity in reducing coronary mortality, according to categories of high, medium, and low caloric output. The age adjusted coronary death rate for the high-activity category is found to be 26.9 per 10,000 work-years, and that for the medium and low categories to be 46.3 and 49.0 respectively. This protective "threshold" effect is seen especially for the sudden death syndrome, in which the death rate for heavy workers is 5.6 as contrasted with 19.9 for moderate and 15.7 for light workers. The conclusion drawn is that repeated bursts of high energy output establish a plateau of protection against coronary mortality, and that several different mechanisms may explain this finding.
Cardiovascular-system-disorders; Mortality-rates; Protective-mechanisms; Etiology; Preventive-medicine; Cargo-handlers; Materials-handling
Issue of Publication
New England Journal of Medicine
Page last reviewed: November 20, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division