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Antihistamine effects on motor skills and vigilance.
Institute of Rehabilitation Medicine, Division of Biomechanics, New York University 1975 Jan; :1-119
Controlled studies were performed to measure the degree and the manner in which performance abilities of 12 females were affected by a nonprescription antihistamine compound, in two simulated industrial work tasks, one requiring vigilance and the other requiring sensory motor function. In the vigilance task, for subjects treated with the antihistamine, the differences in response time to three key lights were not statistically significant, although the investigation validated the hypothesis that missed responses would be statistically significant. Neither false responses nor purposeful eye movements achieved statistical significance. Dependent variables of the motor skills tasks also failed to achieve statistical significance. The results indicate that, for occupational safety and health, active bodily motion should be incorporated into inspection and monitoring tasks, even though such motion could be automated or machined out. Time period was statistically significant for all dependent variables of the vigilance task on the antihistamine day, while in the motor skills task time period was insignificant for all dependent variables.
NIOSH-Grant; Drugs; Statistical-analysis; Alertness; Motor-functions; Task-performance; Human-factors-engineering; Light-stimulation; Motor-visual-performance; Sensory-perceptual-processes; Sensory-mechanisms
Center for Safety New York University 400 East 34 Street New York, N Y 10016
Final Grant Report
NTIS Accession No.
Institute of Rehabilitation Medicine, Division of Biomechanics, New York University
New York University, New York, New York
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division