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Acute bronchitis due to cotton plant polyphenols.
Ann NY Acad Sci 1974 Feb; 221(1):335-339
A concept is presented that airways, particularly distal airways in mammalian lung, are a site for the recognition of foreign materials and response by cell recruitment. Polyphenolic extracts from cotton trash and pure quercetin and oxidation-polymerization products of quercetin when administered as aerosols or on dust recruit polymorphonuclear leukocytes on airways from trachea to terminal bronchioles in hamsters. The method is considered helpful in determining the time and phases of human responses to cotton trash inhalation or byssinosis, and also in appraising other toxic inhalants such as brass fumes or toluene diisocyanate.
NIOSH-Publication; NIOSH-Grant; Respiratory-system-disorders; Dust-control; Airway-obstruction; Cotton-dust; Dust-inhalation; Particulate-dusts; Phenols; Isocyanates; Toxic-substances
Kaye H. Kilburn, Division of Pulmonary and Environmental Medicine, Duke University Medical Center, Durham, North Carolina 27710
Issue of Publication
Annals of the New York Academy of Sciences
University of Missouri Columbia, Columbia, Missouri
Page last reviewed: September 4, 2020
Content source: National Institute for Occupational Safety and Health Education and Information Division