Acute bronchitis due to cotton plant polyphenols.
Ann NY Acad Sci 1974 Feb; 221(1):335-339
A concept is presented that airways, particularly distal airways in mammalian lung, are a site for the recognition of foreign materials and response by cell recruitment. Polyphenolic extracts from cotton trash and pure quercetin and oxidation-polymerization products of quercetin when administered as aerosols or on dust recruit polymorphonuclear leukocytes on airways from trachea to terminal bronchioles in hamsters. The method is considered helpful in determining the time and phases of human responses to cotton trash inhalation or byssinosis, and also in appraising other toxic inhalants such as brass fumes or toluene diisocyanate.
NIOSH-Publication; NIOSH-Grant; Respiratory-system-disorders; Dust-control; Airway-obstruction; Cotton-dust; Dust-inhalation; Particulate-dusts; Phenols; Isocyanates; Toxic-substances
Medicine University of Missouri N424 Medical Center Columbia, MO 65201
Annals of the New York Academy of Sciences
University of Missouri Columbia, Columbia, Missouri