NIOSHTIC-2 Publications Search

Changes in pulmonary function in workers exposed to vinyl chloride and polyvinyl chloride.

Authors
Miller-A; Teirstein-AS; Chuang-M; Selikoff-IJ; Warshaw-R
Source
Ann NY Acad Sci 1975 Jan; 246:42-52
NIOSHTIC No.
00036470
Abstract
Spirometry and maximum expiratory flow-volume curves are obtained in 348 workers in a vinyl-chloride (75014) polymerization plant to determine whether occupational exposure to vinyl-chloride gas and polyvinyl-chloride (9002862) dust is associated with changes in pulmonary function. The major finding is diminution in air flow in 200 workers (57.5 per cent), an abnormality correlated with age and duration of exposure. A relationship with smoking is noted only in younger workers with exposures of less than 10 years. When age exceeds 40 years or exposure 20 years, prevalence of this impairment is similar in smokers and nonsmokers, suggesting that occupational or other environmental factors are operative.
Keywords
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Chlorinated-hydrocarbons; Toxic-gases; Smoking-habits; Epidemiology; Plastics-industry; Polymers
Contact
Community Medicine Mount Sinai School of Medicine Fifth Avenue and 100 Street New York, N Y 10029
CODEN
ANYAA9
CAS No.
75-01-4; 9002-86-2
Publication Date
19750131
Document Type
Journal Article
Funding Amount
629948
Funding Type
Grant
Fiscal Year
1975
Identifying No.
Grant-Number-R01-OH-00320
ISSN
0077-8923
Priority Area
Pulmonary-system-disorders
Source Name
Annals of the New York Academy of Sciences
State
NY
Performing Organization
Mount Sinai School of Medicine, New York, New York
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division