The role of manganese in human disease.
Ann Clin Lab Sci 1974; 4(6):487-491
The role of manganese (7439965) in the human body and its toxic effects as a neurotoxic metal are discussed, with emphasis on susceptibility to manganese poisoning from pollution caused by substitution of manganese for lead as an antiknock agent in gasoline. Similarity of manganese poisoning to parkinsonism is discussed, also treatment and response to levodopa. Manganese is determined to present a hazard to anemic patients and infants, as they lack the normal protection from intestinal and blood brain barriers.
NIOSH-Publication; NIOSH-Grant; Manganism; Transition-metals; Metabolism; Metal-poisoning; Drug-therapy; Neurological-disorders; Brain-disorders
Nuclear Medicine Pan American Hlth Organization 525 23Rd Street, N W Washington, D C 20037
Annals of Clinical and Laboratory Science
Pan American Health Organization, Washington, Dist of Col