Influence of exposure history on mercury excretion.
Final Report, Northwestern University Technological Institute, Evanston, Illinois, 1973 Oct; :1-54
Determination of whether the size of a dose of a given mercurial influences the kinetics of distribution and elimination of the mercury (7439976), based on the great differences in urinary mercury output observed among workers of the same group. Results of the study are considered applicable to strengthening the scientific basis for the bioassay monitoring portion of the occupational health surveillance program designed to prevent damage to exposed workers. The dose dependence of elimination kinetics is studied by injecting labeled mercury at various dose levels into rabbits and rats, measuring the elimination from the animal directly by total body counting techniques and indirectly by analysis of the daily urine and feces output of each animal.
NIOSH-Grant; Time-dose-relationships; Exposure; Dosimetry; Serology; Blood-chemistry; Metal-poisoning; Mercury-poisoning; Biochemical-reactions
Final Grant Report
NTIS Accession No.
Final Report, Northwestern University Technological Institute, Evanston, Illinois, 54 pages