Urinary fluoride levels in polytetrafluoroethylene fabricators.
Polakoff-PL; Busch-KA; Okawa-MT
Am Ind Hyg Assoc J 1974 Feb; 35(2):99-106
Urinary fluoride levels were investigated as an index of polytetrafluoroethylene (PTFE) exposure, since carbonyl fluoride, a pyrolysis product of PTFE, is metabolized and excreted as inorganic fluoride ion, with spot urine samples and occupational histories relating to polymer fume fever obtained from 77 workers at a small PTFE fabricating plant, and environmental air sampling for PTFE. Air levels of PTFE ranging from 0 to 5.48 milligrams per cubic meter were found, all urine values fell below the level at which systemic effects are reported to occur. Analyses of the results by the method of analysis of variance demonstrated that the mean urinary fluoride level among workers who had one or more years of exposure to PTFE who also had experienced one or more reported episodes of polymer fume fever was significantly higher (P is less then 0.01) than that among employees with less than one year or more of exposure and no history of polymer fume fever. Additional exposure beyond one year and additional polymer fume fever episodes did not result in the further elevation of urine fluoride levels.
NIOSH-Author; Screening-tests; PM9002840; Dust-control; Analytical-methods; Urinalysis; Plastics; Fluorocarbons
American Industrial Hygiene Association Journal