Byssinosis in a nontextile worker.
Hamilton-JD; Germino-VH Jr.; Merchant-JA; Lumsden-JC; Kilburn-KH
Am Rev Respir Dis 1973 Mar; 107(3):464-466
Case study of a 32-year-old male with a history of childhood asthma and hay fever but without occupational exposure to the cotton mill environment, exposed to a cotton mill environment to determine the role of atopy in susceptibility, the nature of tolerance to systemic effects of cotton dust, and whether blood gas abnormalities accompany the characteristic bronchoconstriction of byssinosis. Data are given for symptomatic and pulmonary function responses to cotton dust exposure, dust levels in cotton mills, and for changes in the respiratory systems. Acute, profound decreases in forced expiratory volume in one second and arterial oxygen tension are noted within 15 minutes of entering the mill and are correlated with the development of severe shortness of breath. Results indicate that a history of asthma may increase the likelihood of reaction to cotton dust, that a prior period of sensitization to cotton dust is not essential, and that very severe changes in pulmonary flow and arterial oxygenation may occur in a nontextile worker.
NIOSH-Publication; NIOSH-Grant; Dust-control; Respiratory-disorders; Respiratory-function-tests; Dust-inhalation; Testing; Blood-gas-analysis; Respiratory-gas-levels; Air-quality
Division of Environmental Medicine, Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina 27710
American Review of Respiratory Disease
Duke University, Durham, North Carolina