NIOSHTIC-2 Publications Search

Production of tolerance to ozone: an immunochemical phenomenon?

Authors
Mendenhall-RM
Source
Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Consumer Protection and Environmental Health Service, Environmental Control Administration, Bureau of Occupational Safety and Health, RR-13, 1969 Apr; :1-8
Link
NIOSHTIC No.
00020359
Abstract
The immunochemical basis for development of tolerance to ozone through a single nonlethal exposure is studied in animals by observation of serum glycoproteins increase during the course of immunity development, and use of the agar double-diffusion technique for indicating identity or non-identity of precipitating antigen- antibody reactions. No significant increases in tolerance or of serum glycoproteins are observed, nor are additional precipitin lines formed, with results not supporting the immunochemical theory.
Keywords
Toxic-gases; Irritants; Immunology; Analytical-techniques; Serology; Blood-chemical-reactions; Adaptability
CAS No.
10028-15-6
Publication Date
19690401
Document Type
Other
Fiscal Year
1969
Identifying No.
RR-13
NIOSH Division
BOSH
Source Name
Bureau of Occupational Safety and Health
State
OH
Page last reviewed: April 12, 2019
Content source: National Institute for Occupational Safety and Health Education and Information Division