Surface spreading of lung alveolar surfactant.
Respir Physiol 1972 Oct; 16(2):175-178
Indications of the rate of spreading of lung alveolar surfactant (LAS) in the presence of known differentials of surface tension were sought. LAS was found to spread and abolish surface tension differences at a rate measured in centimeters/second whether the initial surface tension differential was relatively high (35 dynes/cm) or low (15 dynes/cm). The laws of capillarity would require surface tension in alveoli to be directly proportional to their size; however, groups of alveoli of varying sizes are contiguous and, forming a single surface, possibly act as a unit with respect to surface tension because of rapid equalization of differences in surface tension. LAS originates its movement in the alveoli and therefore serves as an agent to remove particulate matter from lung alveoli.
Alveolar-cell; Interfacial-tension; Lungs; NIOSH-Author; Surface-active-agent;
Author Keywords: Alveolar surfactant; Lung stability; Removal of particulates; Surface tension; Tracheal surfactant
Richard M. Mendenhall, Department of Health, Education, and Welfare, Public Health Service, National Institute for Occupational Safety and Health, 1014 Broadway, Cincinnati, Ohio 45202, U.S.A.