Alkyl mercury poisoning in humans.
Pierce-PE; Thompson-JF; Likosky-WH; Nickey-LN; Barthel-WF; Hinman-AR
JAMA J Am Med Assoc 1972 Jun; 220(11):1439-1442
Methylmercury poisoning resulting from ingestion of pork from pigs which had been fed grain treated with an alkyl-mercury fungicide is reported in three members of a family of nine. Case histories of three children reveal classic symptoms of methylmercury poisoning progressing to coma or semi-comatose. Treatment with dimercaprol (59529) (British Anti-Lewisite in Oil) and n-acetyl-d,1- penicillamine was not associated with significant immediate clinical improvement, although both drugs appeared to increase urinary excretion of mercury (7439976). All three patients improved considerably but still remain severely impaired. While motor functions improved, visual impairment did not. A case of congenital methylmercury poisoning also resulted from this outbreak which is the first known instance in the United States of methylmercury poisoning resulting from ingestion of mercury-contaminated meat.
Chelation; Fungicide; Heavy-metal; NIOSH-Author
Journal of the American Medical Association