Effect of chronic obstructive pulmonary disease on rate of deposition of aerosols in the lung during breath holding.
Palmes-ED; Goldring-RM; Wang-CS; Altshuler-B
Inhaled Particles III: Proceedings of an International Symposium Organized by the British Occupational Hygiene Society in London, September 14-23, 1970. Walton WH, ed. Old Woking, England: Unwin Brothers Limited, 1971 Jan; 1:123-130
The deposition rate of aerosols during breath holding at different degrees of lung inflation was determined in lung emphysema patients, with or without chronic bronchitis, to determine the effect of alveolar wall destruction and the resultant enlargement of air spaces occurring in these patients. Lung volume at which the breath is held was determined with a "bag in a box" device provided with a system of valves; total lung capacity and residual volume were also determined. The results obtained in diseased and normal individuals demonstrate that determination of aerosol deposition in the lung during breath holding is a promising diagnostic procedure.
NIOSH-Grant; Chronic-obstructive-lung-disease; Lung-emphysema; Chronic-bronchitis; Diagnostic-techniques; Respiratory-function-tests; Respiratory-mechanics
Environmental Medicine New York Univ Med Ctr 550 First Avenue New York, N Y 10016
Inhaled Particles III: Proceedings of an International Symposium Organized by the British Occupational Hygiene Society in London, September 14-23, 1970
New York University, New York, New York