Polyfluoroethylene pyrolysis studies.
Occupational Health Program, National Center for Urban and Industrial Health, Public Health Service, U.S. Department of Health, Education, and Welfare, Cincinnati, Ohio, 1967 Oct; :1-53
In a cooperative series of polyfluoroethylene pyrolysis studies, products generated from the pyrolysis of polytetrafluoroethylene (PTFE) in air were detected, identified, and measured. Both qualitative and quantitative data were collected. Mass spectrometry, gas chromatography, and infrared spectrophotometry were used in qualitative identification. Quantitative determinations were made utilizing atmospheric samples from the animal exposure chamber measured by a modified Bellack and Schouboe method for detection of fluoride in water and by a fluoride electrode to detect hydrolyzable fluoride. Principal toxic products detected were carbonyl fluoride, silicon tetrafluoride, and a particulate residue. The toxic syndrome produced in experimental animals due to inhalation of pyrolysis products of PTFE is compatible with the description of fluoride poisoning in humans.
Biochemistry; Blood; Fluorinated-ethylenes; Toxicity; Decomposition; Equipment; Plastics; Lethality; Evaluation; Pathology; Metabolism; Injury; Lungs; Liver; PM9002840
353-50-4; 7783-61-1; 7732-18-5
Occupational Health Program, National Center for Urban and Industrial Health, Public Health Service, U.S. Department of Health, Education, and Welfare, Cincinnati, Ohio, Report No. TR-47, 53 pages, 51 references