Immediately Dangerous to Life or Health (IDLH) Value Profile: Chlorine Trifluoride (CAS® No. 7790-91-2)
July 2020
DHHS (NIOSH) Publication Number 2020-124
Overview of the IDLH Value for Chlorine Trifluoride
IDLH Value: 12 ppm (45 mg/m3)
Basis for IDLH Value: The IDLH value for chlorine trifluoride (CIF3) is based on data on eye irritation in rats exposed at a concentration of 480 ppm for 5 minutes, which was determined to be escape-impairing [Horn and
Weir 1955]. The duration adjusted 30-minute concentration is 121 ppm. An uncertainty factor (UF) of 10 was applied to account for interspecies variability (factor of 3) and human variability (factor of 3), resulting in a derived IDLH value of 12 ppm.
Purpose
This IDLH Value Profile presents (1) a brief summary of technical data associated with acute inhalation exposures to ClF3, and (2) the rationale behind the immediately dangerous to life or health (IDLH) value for ClF3. IDLH values are developed on the basis of the scientific rationale and logic outlined in the NIOSH Current Intelligence Bulletin (CIB) 66: Derivation of Immediately Dangerous to Life or Health (IDLH) Values [NIOSH 2013].
Suggested Citation
NIOSH [2020]. Immediately dangerous to life or health (IDLH) value profile: chlorine trifluoride, CAS® No. 7790-91-2. By Niemeier RT. Cincinnati, OH: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2020-124, https://doi.org/10.26616/NIOSHPUB2020124