Propylamine

RTECS #

UH9100000

CAS #

107-10-8
See: NMAM or OSHA Methods

Updated

July 2011

Molecular Weight

59.13

Molecular Formula

C₃H₉N

Synonyms

1-Aminopropane
1-Propanamine
1-Propylamine
Mono-n-propylamine
Monopropylamine
n-Propylamine
Propanamine
RCRA waste number U194

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /rabbit	720 µg	severe	UCDS** 8/12/1968
skin /rabbit	100 µg/24H open irritation test		AIHAAP 23,95,1962

Route/Organism	Dose	Effect	Reference
In Vitro/Human, liver tumor	Inhibitor Concentration (50 percent kill): 11 mmol/L/24H	In Vitro Toxicity Studies: Cell protein synthesis	TIVIEQ 3,189,1989
inhalation/mammal (species unspecified)	lethal concentration (50 percent kill): 2500 mg/m³		TPKVAL 14,80,1975
inhalation/mouse	lethal concentration (50 percent kill): 2500 mg/m³/2H		85GMAT -,102,1982
inhalation/rat	lethal concentration (50 percent kill): 2310 ppm/4H	Lung, Thorax, or Respiration: Dyspnea Liver: Hepatitis (hepatocellular necrosis), diffuse	AEHLAU 1,343,1960
intraperitoneal/rat	lowest published lethal dose: 37500 µg/kg		FATOAO 31,238,1968
oral/rat	lethal dose (50 percent kill): 370 mg/kg		NTIS** OTS0535430
skin/rabbit	lethal dose (50 percent kill): 400 mg/kg		NTIS** OTS0535430
unreported route/mammal (species unspecified)	lethal dose (50 percent kill): 580 mg/kg		TPKVAL 14,80,1975

Route/Organism	Dose	Effect	Reference
inhalation/rat	lowest published toxic concentration: 400 ppm/7H/50D- intermittent	Nutritional and Gross Metabolic: Weight loss or decreased weight gain Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field	AEHLAU 1,343,1960

Organization	Standard	Reference
TOXICOLOGY REVIEW		CHREAY 9,389,1931

Organization	Standard	Reference
Occupational Exposure Limit-RUSSIA	short term exposure limit 5 mg/m³, JUN2003

Organization	Standard	Reference
National Occupational Exposure Survey 1983	Hazard Code 83632; Number of Industries 1; Total Number of Facilities 7; Number of Occupations 1; Total Number of Employees Exposed 28
National Occupational Hazard Survey 1974	Hazard Code 83632; Number of Industries 3; Total Number of Facilities 339; Number of Occupations 7; Total Number of Employees Exposed 1723

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

Page last reviewed: November 16, 2018