2-Propanol, 1-amino-
RTECS #
UA5775000
CAS #
Updated
August 2006
Molecular Weight
75.13
Molecular Formula
C3H9NO
Synonyms
1-Amino-2-propanol
1-Aminopropan-2-ol
1-Methyl-2-aminoethanol
2-Hydroxy-1-propylamine
2-Hydroxypropylamine
alpha-Aminoisopropyl alcohol
Isopropanolamine
Mono-iso-propanolamine
Threamine
1-Aminopropan-2-ol
1-Methyl-2-aminoethanol
2-Hydroxy-1-propylamine
2-Hydroxypropylamine
alpha-Aminoisopropyl alcohol
Isopropanolamine
Mono-iso-propanolamine
Threamine
Skin and Eye Irritation and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
eye /rabbit | 970 µg | severe | UCDS** 5/21/1971 |
eye /rabbit | 250 µg/24H | severe | 85JCAE -,683,1986 |
skin /rabbit | 485 mg open irritation test | moderate | UCDS** 5/21/1971 |
skin /rabbit | 500 mg/24H | mild | 85JCAE -,683,1986 |
Reproductive Effects Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
unreported route/rat | 280 µg/kg (1D male) | Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea) | TLSMA6 140,79,1981 |
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
intraperitoneal/mouse | lowest published lethal dose: 250 mg/kg | Behavioral: Excitement | CBCCT* 4,232,1952 |
oral/rat | lethal dose (50 percent kill): 1715 mg/kg | Behavioral: Somnolence (general depressed activity) Gastrointestinal: Hypermotility, diarrhea Nutritional and Gross Metabolic: Body temperature decrease | GTPZAB 30(7),46,1986 |
skin/mammal (species unspecified) | lethal dose (50 percent kill): >1 gm/kg | GTPZAB 30(7),46,1986 | |
skin/rabbit | lethal dose (50 percent kill): 1640 µL/kg | UCDS** 5/21/1971 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Occupational Exposure Limit-RUSSIA | short term exposure limit 1 mg/m3, Skin, JUN2003 |
NIOSH Documentation and Surveillance
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
EPA TSCA Section 8(d) unpublished health/safety studies | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health