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The National Institute for Occupational Safety and Health (NIOSH)

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Registry of Toxic Effects of Chemical Substances (RTECS)

1,2-Propanediol, diacetate

RTECS #

TY4900000

CAS #

623-84-7

Updated

August 2006

Molecular Weight

160.19

Molecular Formula

C₇H₁₂O₄

Synonyms

alpha-Propylene glycol diacetate
Propylene glycol diacetate

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /rabbit	500 mg	moderate	AJOPAA 29,1363,1946
skin /human	107 mg/3D- intermittent	mild	85DKA8 -,127,1977

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
oral/guinea pig	lethal dose (50 percent kill): 3420 mg/kg	Behavioral: General anesthetic Gastrointestinal: Other changes Kidney, Ureter, and Bladder: Other changes	JIHTAB 23,259,1941
oral/rat	lethal dose (50 percent kill): 13530 mg/kg		JIHTAB 23,259,1941

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Occupational Hazard Survey 1974	Hazard Code M2739; Number of Industries 1; Total Number of Facilities 112; Number of Occupations 4; Total Number of Employees Exposed 2016

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY

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Page last reviewed:March 7, 2014
Page last updated:February 6, 2017
Content source:
- National Institute for Occupational Safety and Health (NIOSH) Education and Information Division

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