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Registry of Toxic Effects of Chemical Substances (RTECS)

Phosphorothioic acid, O,O-diethyl O-(1,2,2,2-tetrachloroethyl) ester

RTECS #

TF6150000

CAS #

54593-83-8; 104559-35-5; 119791-49-0

Updated

December 2015

Molecular Weight

336.00

Molecular Formula

C6H11Cl4O3PS

Synonyms

Chloroethoxyfos
Chloroethoxyphos
DPX 43898
Fortress
O,O-Diethyl O-(1,2,2,2-tetrachloroethyl) phosphorothioate
SD 208304

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat lethal concentration (50 percent kill): 400 ppbFMCHA2 -,C146,1991
oral/chicken lethal dose (50 percent kill): 14 mg/kgBehavioral: Tremor

Behavioral: Ataxia

Gastrointestinal: Changes in structure or function of salivary glands
NTIS** OTS0530328
oral/rat lethal dose (50 percent kill): 2 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)

Gastrointestinal: Changes in structure or function of salivary glands
NTIS** OTS0536238
skin/rabbit lethal dose (50 percent kill): 12500 µg/kgFMCHA2 -,C146,1991
unreported route/rat lethal dose (50 percent kill): 1800 µg/kgFMCHA2 -,C146,1991

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/Dog lowest published toxic dose: 9 mg/kg/26W- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesteraseTOXID9 30,124,1996

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWREPTED 31,392,2011
TOXICOLOGY REVIEWTOLED5 230,434,2014

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESActive registrationRBREV* -,358,1998

Status in Federal Agencies

OrganizationReference
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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