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Registry of Toxic Effects of Chemical Substances (RTECS)

1,3-Indandione, 2-pivaloyl-

RTECS #

NK6300000

CAS #

83-26-1

Updated

September 2013

Molecular Weight

230.28

Molecular Formula

C14H14O3

Synonyms

1,3-Indandione, 2-pivalyl-
2-(2,2-Dimethyl-1-oxopropyl)-1H-indene-1,3(2H)-dione
2-(Trimetil-acetil)-indan-1,3-dione (Italian)
2-Pivaloyl-1,3-indandione
2-Pivaloyl-indaan-1,3-dion (Dutch)
2-Pivaloyl-indan-1,3-dion (German)
2-Pivaloylindane-1,3-dione
2-Pivalyl-1,3-indandione (OSHA)
2-Trimethylacetyl-1,3-indandione
Chemrat
Contrax-P
Latka 333 (Czech)
Paracakes
Para-Pac
Pindon (Dutch)
Pindone
Pindone (ACGIH:OSHA)
Pivacin
Pival (OSHA)
Pivaldion (Italian)
Pivaldione (French)
Pivalyl valone
Tri-ban

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intravenous/rat lethal dose (50 percent kill): 50 mg/kgYKYUA6 31,1385,1980
oral/Dog lethal dose (50 percent kill): 75 mg/kg85GYAV -,118,1971
oral/domestic animal lowest published lethal dose: 75 mg/kgAWLRAO 5,135,1978
oral/rabbit lethal dose (50 percent kill): 150 mg/kg85DPAN -,-,1971/1976
oral/rat lethal dose (50 percent kill): 280 mg/kgBehavioral: Tremor

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement
TXAPA9 2,88,1960
parenteral/rat lethal dose (50 percent kill): 50 mg/kgGUCHAZ 6,415,1973

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
oral/domestic animal lowest published toxic dose: 85400 µg/kg/7D- continuousBehavioral: Food intake (animal)

Blood: Change in clotting factors
AWLRAO 5,135,1978
oral/rabbit lowest published toxic dose: 350 µg/kg/7D- continuousBlood: Hemorrhage

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
AWLRAO 5,135,1978

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.1 mg/m3DTLVS* TLV/BEI,2013
TOXICOLOGY REVIEWVHTODE 43,353,2001
TOXICOLOGY REVIEWHUTOX* -,561,1996

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESRED CompletedRBREV* -,202,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.1 mg/m3DTLVS* 3,213,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.1 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 0.1 mg/m3;KZW 0.2 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 0.1 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.1 mg/m3, MAY2011
Occupational Exposure Limit-FRANCEVME 0.1 mg/m3, FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 0.1 mg/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 0.1 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.1 mg/m3;short term exposure limit 0.3 mg/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.1 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.1 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 0,1 mg/m3, JUL2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.1 mg/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.1 mg/m3, 2003
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.1 mg/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.1 mg/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.1 mg/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.1 mg/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PINDONE-air10H time-weighted average 0.1 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 60110; Number of Industries 7; Total Number of Facilities 769; Number of Occupations 9; Total Number of Employees Exposed 6855; Total Number of Female Employees Exposed 1432

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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