Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Registry of Toxic Effects of Chemical Substances (RTECS)

Ethane, 1,1-dichloro-1-nitro-

RTECS #

KI1050000

CAS #

594-72-9

Updated

September 2013

Molecular Weight

143.96

Molecular Formula

C2H3Cl2NO2

Synonyms

1,1-Dichloor-1-nitroethaan (Dutch)
1,1-Dichlor-1-nitroaethan (German)
1,1-Dichloro-1-nitroethane
1,1-Dichloro-1-nitroethane (ACGIH:OSHA)
1,1-Dicloro-1-nitroetano (Italian)
Dichloronitroethane
Ethide

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium333 µg/plate (-enzymatic activation step)EMMUEG 19(Suppl 21),2,1992

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/guinea pig Lowest published lethal concentration: 580 mg/m3/6HEye: Lacrimation

Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Cough
JIHTAB 27,95,1945
inhalation/rabbit Lowest published lethal concentration: 580 mg/m3/6HEye: Lacrimation

Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Cough
JIHTAB 27,95,1945
intraperitoneal/mouse lethal dose (50 percent kill): 240 mg/kgKHFZAN 10(6),53,1976
oral/rabbit lowest published lethal dose: 150 mg/kgVascular: Other changes

Lung, Thorax, or Respiration: Acute pulmonary edema

Gastrointestinal: Ulceration or bleeding from stomach
JIHTAB 27,95,1945
oral/rat lethal dose (50 percent kill): 410 mg/kgBESAAT 12,161,1966

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 2 ppmDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARDair-ceiling concentration 10 ppm (60 mg/m3)DTLVS* 3,82,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 2 ppm (12 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 2 ppm (12 mg/m3), skin, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 2 ppm (12 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKceiling concentration 2 ppm (12 mg/m3), MAY2011
Occupational Exposure Limit-FINLANDtime-weighted average 10 ppm (60 mg/m3), short term exposure limit 20 ppm (120 mg/m3), NOV2011
Occupational Exposure Limit-FRANCEVME 2 ppm (10 mg/m3), FEB2006
Occupational Exposure Limit-ICELANDshort term exposure limit 2 ppm (12 mg/m3), NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 2 ppm (10 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 2 ppm (10 mg/m3);short term exposure limit 10 ppm (60 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 2 ppm (12 mg/m3), JAN2002
Occupational Exposure Limit-PERUtime-weighted average 2 ppm (12 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 30 mg/m3, MAC(short term exposure limit) 60 mg/m3, JAN1999
Occupational Exposure Limit-SWITZERLANDMAK-week 2 ppm (12 mg/m3), JAN2011
Occupational Exposure Limit-THAILANDtime-weighted average 10 ppm (60 mg/m3), JAN1993
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 10 ppm (60 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 10 ppm (60 mg/m3), JAN1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)ceiling concentration 10 ppm (60 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)ceiling concentration 10 ppm (60 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)ceiling concentration 10 ppm (60 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)ceiling concentration 10 ppm (60 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO 1,1-DICHLORO-1-NITROETHANE-air10H time-weighted average 2 ppmNIOSH* DHHS #92-100,1992

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: 1,1-Dichloro-1-nitroethane, 1601
TOP