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Registry of Toxic Effects of Chemical Substances (RTECS)

Boron oxide

RTECS #

ED7900000

CAS #

1303-86-2

Updated

September 2013

Molecular Weight

69.62

Molecular Formula

B2O3

Synonyms

Boric anhydride
Boron oxide (ACGIH:OSHA)
Boron oxide, aerosol
Boron sesquioxide
Boron trioxide
Diboron trioxide
Fused boric acid

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 50 mgAIHAAP 20,284,1959
skin /rabbit 1 gmAIHAAP 20,284,1959

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
inhalation/rat Lowest published lethal concentration: 150 mg/m3/2HVCVN1* -,193,1988
intraperitoneal/mouse lethal dose (50 percent kill): 1868 mg/kgVCVN1* -,193,1988
oral/mouse lethal dose (50 percent kill): 3163 mg/kgVCVN1* -,193,1988
oral/rat lethal dose (50 percent kill): 3150 mg/kgVCVN1* -,193,1988

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/Dog lowest published toxic concentration: 57 mg/m3/23W- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Incontinence
VCVN1* -,194,1988
inhalation/rat lowest published toxic concentration: 77 mg/m3/6H/24W- intermittentKidney, Ureter, and Bladder: Urine volume increased

Kidney, Ureter, and Bladder: Other changes in urine composition
AIHAAP 20,284,1959
inhalation/rat lowest published toxic concentration: 150 mg/m3/2H/15D- intermittentOlfaction: Other olfaction effects

Lung, Thorax, or Respiration: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVN1* -,194,1988
inhalation/rat lowest published toxic concentration: 470 mg/m3/24W- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Incontinence
VCVN1* -,194,1988

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 10 mg/m3DTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESRED CompletedRBREV* -,91,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 10 mg/m3DTLVS* 3,26,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 10 mg/m3, JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 15 mg/m3;KZW 75 mg/m3, inhal, 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 10 mg/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 10 mg/m3, MAY2011
Occupational Exposure Limit-FRANCEVME 10 mg/m3, FEB2006
Occupational Exposure Limit-ICELANDtime-weighted average 10 mg/m3, NOV2011
Occupational Exposure Limit-KOREAtime-weighted average 10 mg/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 10 mg/m3;short term exposure limit 20 mg/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 10 mg/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 10 mg/m3, JAN1999
Occupational Exposure Limit-PERUtime-weighted average 10 mg/m3, JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 10 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAshort term exposure limit 5 mg/m3, JUN2003
Occupational Exposure Limit-SWITZERLANDMAK-week 10 mg/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 15 mg/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 10 mg/m3;short term exposure limit 20 mg/m3, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 15 mg/m3, total dustCFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 15 mg/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 15 mg/m3, total dustCFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 15 mg/m3, total dustCFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 5 mg/m3, respirable fractionCFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BORON OXIDE, total dust-air10H time-weighted average 10 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 12963; Number of Industries 112; Total Number of Facilities 10437; Number of Occupations 78; Total Number of Employees Exposed 162342; Total Number of Female Employees Exposed 18457
National Occupational Hazard Survey 1974Hazard Code 12963; Number of Industries 69; Total Number of Facilities 2563; Number of Occupations 49; Total Number of Employees Exposed 15319

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
On EPA IRIS database
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