Benzoic acid, benzyl ester
RTECS #
DG4200000
CAS #
Updated
September 2018
Molecular Weight
212.26
Molecular Formula
C14H12O2
Synonyms
Ascabin
Ascabiol
Benylate
Benzoic acid, phenylmethyl ester
Benzyl alcohol benzoic ester
Benzyl benzenecarboxylate
Benzyl benzoate
Benzyl phenylformate
Benzylester kyseliny benzoove (Czech)
Benzylets
Colebenz
Novoscabin
Peruscabin
Scabanca
Vanzoate
Venzonate
Ascabiol
Benylate
Benzoic acid, phenylmethyl ester
Benzyl alcohol benzoic ester
Benzyl benzenecarboxylate
Benzyl benzoate
Benzyl phenylformate
Benzylester kyseliny benzoove (Czech)
Benzylets
Colebenz
Novoscabin
Peruscabin
Scabanca
Vanzoate
Venzonate
Acute Toxicity Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
In Vitro/Human, lymphocyte | Inhibitor Concentration (30 percent kill): >200 mg/L/45H | In Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc. | TIVIEQ 29,901,2015 |
In Vitro/Human, lymphocyte | Inhibitor Concentration (50 percent kill): >200 mg/L/45H | In Vitro Toxicity Studies: Other assays | TIVIEQ 29,901,2015 |
In Vitro/Mouse, fibroblast | Inhibitor Concentration (50 percent kill): >11.8 mmol/L/48H | In Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc. | TIVIEQ 27,1357,2013 |
In Vitro/paa | Inhibitor Concentration Low: 124 µmol/L/44H | In Vitro Toxicity Studies: Other assays | TIVIEQ 27,1416,2013 |
inhalation/mouse | lowest published toxic concentration: 2 pph/10M | Brain and Coverings: Other degenerative changes Behavioral: Antianxiety Biochemical: Neurotransmitters or modulators (putative): Dopamine in striatum | PYTOEY 23,1734,2016 |
intraperitoneal/mouse | lethal dose (50 percent kill): >500 mg/kg | 14CYAT 2,1897,1963 | |
oral/cat | lethal dose (50 percent kill): 2240 mg/kg | Behavioral: Tremor Behavioral: Muscle weakness Gastrointestinal: Changes in structure or function of salivary glands | JPETAB 84,358,1945 |
oral/cat | lethal dose (50 percent kill): 2240 mg/kg | Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Dyspnea | HPV141 -,-,2001 |
oral/Dog | lethal dose (50 percent kill): >22440 mg/kg | HPV141 -,-,2001 | |
oral/guinea pig | lethal dose (50 percent kill): 1 mL/kg | HPV141 -,-,2001 | |
oral/mouse | lethal dose (50 percent kill): 1.4 mL/kg | HPV141 -,-,2001 | |
oral/rabbit | lethal dose (50 percent kill): 1.8 mL/kg | HPV141 -,-,2001 | |
oral/rabbit | lethal dose (50 percent kill): 1680 mg/kg | FCTXAV 11,1015,1973 | |
oral/rabbit | lethal dose (50 percent kill): 1680 mg/kg | Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Dyspnea | HPV141 -,-,2001 |
oral/rat | lethal dose (50 percent kill): 2800 mg/kg | Behavioral: Convulsions or effect on seizure threshold Lung, Thorax, or Respiration: Dyspnea | HPV141 -,-,2001 |
oral/rat | lethal dose (50 percent kill): >1 gm/kg | ENTOX* -,264,2005 | |
oral/rat | lethal dose (50 percent kill): 1.7 mL/kg | HPV141 -,-,2001 | |
skin/rabbit | lethal dose (50 percent kill): 4 gm/kg | FCTXAV 11,1015,1973 | |
skin/rat | lethal dose (50 percent kill): 4 mL/kg | HPV141 -,-,2001 |
Other Multiple Dose Data and References
Route/Organism | Dose | Effect | Reference |
---|---|---|---|
skin/rabbit | lowest published toxic dose: 180 mL/kg/13W- intermittent | Behavioral: Muscle weakness Nutritional and Gross Metabolic: Weight loss or decreased weight gain Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field | JPETAB 93,26,1948 |
skin/rabbit | lowest published toxic dose: 180 mL/kg/90D- intermittent | Brain and Coverings: Encephalitis Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field Related to Chronic Data: Changes in testicular weight | HPV141 -,-,2001 |
skin/rat | lowest published toxic dose: 60000 mg/kg/30D- intermittent | Behavioral: Tremor Skin: After systemic exposure: Dermatitis, other | HPV141 -,-,2001 |
Reviews
Organization | Standard | Reference |
---|---|---|
TOXICOLOGY REVIEW | ENTOX* -,264,2005 |
Standards and Regulations
Organization | Standard | Reference |
---|---|---|
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION | FEREAC 54,7740,1989 | |
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES | Supported | RBREV* -,297,1998 |
Occupational Exposure Limit-RUSSIA | short term exposure limit 5 mg/m3, JUN2003 |
NIOSH Documentation and Surveillance
Status in Federal Agencies
Organization | Reference |
---|---|
EPA TSCA Section 8(b) CHEMICAL INVENTORY |
Page last reviewed: November 16, 2018
Content
source: National Institute for Occupational Safety and Health