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Registry of Toxic Effects of Chemical Substances (RTECS)

Benzene, 2,4-dichloro-1-nitro-

RTECS #

CZ5420000

CAS #

611-06-3

Updated

March 2014

Molecular Weight

192.00

Molecular Formula

C6H3Cl2NO2

Synonyms

2,4-Dichloronitrobenzene

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
mutation in microorganisms/Salmonella typhimurium1 mg/plate (+enzymatic activation step)SAIGBL 29,34,1987
mutation in microorganisms/Salmonella typhimurium3 µg/plate (-enzymatic activation step)ENMUDM 5(Suppl 1),3,1983

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Human, skin Inhibitor Concentration (50 percent kill): 8.2 µmol/L/48HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TXAPA9 245,281,2010
In Vitro/Human, skin Inhibitor Concentration (50 percent kill): 2.5 µmol/L/48HIn Vitro Toxicity Studies: Other assaysTXAPA9 245,281,2010

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWMUREAV 741,32,2012

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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