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Registry of Toxic Effects of Chemical Substances (RTECS)

Barium(II) nitrate (1:2)

RTECS #

CQ9625000

CAS #

10022-31-8

Updated

September 2013

Molecular Weight

261.36

Molecular Formula

N2O6·Ba

Synonyms

Barium dinitrate
Dusicnan barnaty (Czech)
Nitrate de baryum (French)
Nitric acid, barium salt

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H moderate28ZPAK -,10,1972
skin /rabbit 500 mg/24H mild28ZPAK -,10,1972

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Chicken, neurons Inhibitor Concentration (50 percent kill): 4810 µmol/L/21HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (10 percent kill): 2681 µmol/L/21HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (50 percent kill): 4630 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (10 percent kill): 2600 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 7,653,1993
intraperitoneal/mouse lethal dose (50 percent kill): 293 mg/kgAutonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
intraperitoneal/rat lethal dose (50 percent kill): 293 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Tetany
VCVN1* -,136,1988
intravenous/mouse lethal dose (50 percent kill): 16 mg/kgTXAPA9 22,150,1972
oral/Dog lowest published lethal dose: 800 mg/kgYKYUA6 31,1247,1980
oral/mammal (species unspecified) lethal dose (50 percent kill): 390 mg/kgAutonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
oral/man lowest published toxic dose: 83 mg/kgPeripheral Nerve and Sensation: Paresthesia

Behavioral: Muscle weakness

Nutritional and Gross Metabolic: Changes in: K
JTCTDW 38,254,2000
oral/mouse lethal dose (50 percent kill): 266 mg/kgEVHPAZ 106(Suppl 2),497,1998
oral/rabbit lowest published lethal dose: 150 mg/kgYKYUA6 31,1247,1980
oral/rat lethal dose (50 percent kill): 355 mg/kg28ZPAK -,10,1972
oral/rat lethal dose (50 percent kill): 390 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Tetany
VCVN1* -,136,1988
parenteral/rabbit lowest published lethal dose: 30 mg/kgGastrointestinal: Hypermotility, diarrhea

Kidney, Ureter, and Bladder: Urine volume increased
MELAAD 30,44,1939
subcutaneous/mouse lowest published lethal dose: 10 mg/kgNTIS** AEC-TR-6710

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 mg(Ba)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.5 mg(Ba)/m3DTLVS* 3,21,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.5 mg(Ba)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.5 mg(Ba)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg(Ba)/m3, MAY2011
Occupational Exposure Limit-ECtime-weighted average 0.5 mg(Ba)/m3, FEB2006
Occupational Exposure Limit-FINLANDtime-weighted average 0.5 mg(Ba)/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 0.5 mg(Ba)/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.5 mg(Ba)/m3, short term exposure limit 2 mg(Ba)/m3, SEP2000
Occupational Exposure Limit-KOREAtime-weighted average 0.5 mg(Ba)/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg(Ba)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.5 mg(Ba)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit-POLANDtime-weighted average 0.5 mg(Ba)/m3, short term exposure limit 1.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.5 mg/m3, short term exposure limit 1.5 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 0.5 mg(Ba)/m3, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.5 mg(Ba)/m3, KZG-week 1 mg(Ba)/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.5 mg(Ba)/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.5 mg(Ba)/m3, sen, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 81720; Number of Industries 23; Total Number of Facilities 600; Number of Occupations 26; Total Number of Employees Exposed 19320; Total Number of Female Employees Exposed 5165
National Occupational Hazard Survey 1974Hazard Code 81720; Number of Industries 12; Total Number of Facilities 542; Number of Occupations 13; Total Number of Employees Exposed 2705

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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