Barium(II) nitrate (1:2)

RTECS #
CQ9625000
CAS #
10022-31-8
See: NMAM or OSHA Methods
Updated
September 2013
Molecular Weight
261.36
Molecular Formula
N2O6·Ba
Synonyms
Barium dinitrate
Dusicnan barnaty (Czech)
Nitrate de baryum (French)
Nitric acid, barium salt

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H moderate28ZPAK -,10,1972
skin /rabbit 500 mg/24H mild28ZPAK -,10,1972

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Chicken, neurons Inhibitor Concentration (50 percent kill): 4810 µmol/L/21HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (10 percent kill): 2681 µmol/L/21HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (50 percent kill): 4630 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (10 percent kill): 2600 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 7,653,1993
intraperitoneal/mouse lethal dose (50 percent kill): 293 mg/kgAutonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
intraperitoneal/rat lethal dose (50 percent kill): 293 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Tetany
VCVN1* -,136,1988
intravenous/mouse lethal dose (50 percent kill): 16 mg/kgTXAPA9 22,150,1972
oral/Dog lowest published lethal dose: 800 mg/kgYKYUA6 31,1247,1980
oral/mammal (species unspecified) lethal dose (50 percent kill): 390 mg/kgAutonomic Nervous System: Other (direct) parasympathomimetic

Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
oral/man lowest published toxic dose: 83 mg/kgPeripheral Nerve and Sensation: Paresthesia

Behavioral: Muscle weakness

Nutritional and Gross Metabolic: Changes in: K
JTCTDW 38,254,2000
oral/mouse lethal dose (50 percent kill): 266 mg/kgEVHPAZ 106(Suppl 2),497,1998
oral/rabbit lowest published lethal dose: 150 mg/kgYKYUA6 31,1247,1980
oral/rat lethal dose (50 percent kill): 355 mg/kg28ZPAK -,10,1972
oral/rat lethal dose (50 percent kill): 390 mg/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Tetany
VCVN1* -,136,1988
parenteral/rabbit lowest published lethal dose: 30 mg/kgGastrointestinal: Hypermotility, diarrhea

Kidney, Ureter, and Bladder: Urine volume increased
MELAAD 30,44,1939
subcutaneous/mouse lowest published lethal dose: 10 mg/kgNTIS** AEC-TR-6710

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 0.5 mg(Ba)/m3DTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013

Standards and Regulations

OrganizationStandardReference
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 0.5 mg(Ba)/m3DTLVS* 3,21,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 0.5 mg(Ba)/m3, JUL2008
Occupational Exposure Limit-BELGIUMtime-weighted average 0.5 mg(Ba)/m3, MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 0.5 mg(Ba)/m3, MAY2011
Occupational Exposure Limit-ECtime-weighted average 0.5 mg(Ba)/m3, FEB2006
Occupational Exposure Limit-FINLANDtime-weighted average 0.5 mg(Ba)/m3, NOV2011
Occupational Exposure Limit-FRANCEVME 0.5 mg(Ba)/m3, FEB2006
Occupational Exposure Limit-HUNGARYtime-weighted average 0.5 mg(Ba)/m3, short term exposure limit 2 mg(Ba)/m3, SEP2000
Occupational Exposure Limit-KOREAtime-weighted average 0.5 mg(Ba)/m3, 2006
Occupational Exposure Limit-MEXICOtime-weighted average 0.5 mg(Ba)/m3, 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 0.5 mg(Ba)/m3, JAN2002
Occupational Exposure Limit-NORWAYtime-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit-POLANDtime-weighted average 0.5 mg(Ba)/m3, short term exposure limit 1.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 0.5 mg/m3, short term exposure limit 1.5 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 0.5 mg(Ba)/m3, JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 0.5 mg(Ba)/m3, KZG-week 1 mg(Ba)/m3, inhal, JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 0.5 mg(Ba)/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 0.5 mg(Ba)/m3, JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 0.5 mg(Ba)/m3, sen, OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 0.5 mg(Ba)/m3CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code 81720; Number of Industries 23; Total Number of Facilities 600; Number of Occupations 26; Total Number of Employees Exposed 19320; Total Number of Female Employees Exposed 5165
National Occupational Hazard Survey 1974Hazard Code 81720; Number of Industries 12; Total Number of Facilities 542; Number of Occupations 13; Total Number of Employees Exposed 2705

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Page last reviewed: November 16, 2018