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Registry of Toxic Effects of Chemical Substances (RTECS)

Ammonium, dimethyldioctadecyl-, chloride

RTECS #

BQ1923000

CAS #

107-64-2; 76723-98-3

Updated

December 2015

Molecular Weight

586.64

Molecular Formula

C38H80N·Cl

Synonyms

1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride (9CI)
Aliquat 207
Arosurf TA 100
Arquad R 40
Dimethyldioctadecylammonium chloride
Distearyl dimethylammonium chloride
Genamin DSAC
KD 83
N,N-Dimethyl-N-octadecyl-1-octadecanaminium chloride
Q-D 86P
Quaternium 5
Talofloc
Varisoft 100

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Human, melanoma Inhibitor Concentration (50 percent kill): 12.4 mg/L/48HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.FCTOD7 50,2084,2012
In Vitro/jdaInhibitor Concentration (50 percent kill): 246851 mg/L/1HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TOLED5 212,198,2012
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 12.3 µmol/L/48HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 27,1357,2013
In Vitro/paaInhibitor Concentration Low: 5.85 µmol/L/44HIn Vitro Toxicity Studies: Other assaysTIVIEQ 27,1416,2013
In Vitro/Rabbit, ocular Inhibitor Concentration (50 percent kill): 0.003 gm/L/10MIn Vitro Toxicity Studies: Cell Viability (cell death), unspecified assayTIVIEQ 3,329,1989
In Vitro/Rabbit, ocular Inhibitor Concentration Low: 5 pph/5MIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 27,1855,2013
oral/rat lethal dose (50 percent kill): 11300 mg/kgBehavioral: Somnolence (general depressed activity)

Gastrointestinal: Hypermotility, diarrhea

Skin and Appendages: Other: Hair
ESKHA5 (101),152,1983

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code M1155; Number of Industries 12; Total Number of Facilities 2730; Number of Occupations 12; Total Number of Employees Exposed 21120; Total Number of Female Employees Exposed 7716
National Occupational Hazard Survey 1974Hazard Code M1155; Number of Industries 9; Total Number of Facilities 1468; Number of Occupations 8; Total Number of Employees Exposed 6913

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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