Acetic acid, phenyl-

RTECS #
AJ2430000
CAS #
103-82-2
See: NMAM or OSHA Methods
Updated
December 2017
Molecular Weight
136.16
Molecular Formula
C8H8O2
Synonyms
alpha-Toluic acid
Benzenacetic acid
Benzeneacetic acid
Kyselina fenyloctova (Czech)
omega-Phenylacetic acid
Phenylacetic acid

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg/24H moderateNTIS** OTS0559218

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
oral/rat 450 mg/kg (4D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
VPITAR 32,50,1973
oral/rat 19500 mg/kg (14D pre-4D after birth)Reproductive: Other effects on femaleHPV133 -,-,2002
oral/rat 39000 mg/kg (14D pre-4D after birth)Reproductive: Other effects on female

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)
HPV133 -,-,2002

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
intraperitoneal/mouse lethal dose (50 percent kill): 2270 mg/kgFRPSAX 13,286,1958
intraperitoneal/rat lethal dose (50 percent kill): 1600 mg/kgBCFAAI 112,53,1973
oral/guinea pig lethal dose (50 percent kill): 2250 mg/kgVPITAR 33(5),48,1974
oral/mouse lethal dose (50 percent kill): 2250 mg/kgVPITAR 33(5),48,1974
oral/rat lethal dose (50 percent kill): 2250 mg/kgVPITAR 33(5),48,1974
skin/rabbit lethal dose (50 percent kill): >5 gm/kgFCTXAV 13,901,1975
subcutaneous/mouse lethal dose (50 percent kill): 1500 mg/kgAIPTAK 116,154,1958

Reviews

OrganizationStandardReference
TOXICOLOGY REVIEWNETEEC 52,25,2015

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Occupational Exposure Survey 1983Hazard Code X4045; Number of Industries 12; Total Number of Facilities 1636; Number of Occupations 37; Total Number of Employees Exposed 19331; Total Number of Female Employees Exposed 6627

Status in Federal Agencies

OrganizationReference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
Page last reviewed: November 16, 2018