Castor oil

RTECS #

FI4100000

CAS #

8001-79-4; 8021-37-2
See: NMAM or OSHA Methods

Updated

March 2018

Molecular Weight

N/R

Molecular Formula

N/R

Synonyms

Aromatic castor oil
Castor oil aromatic
Cosmetol
Crystal O
Gold bond
NCI-C55163
Neoloid
Oil of Palma christi
Phorbyol
Ricinus oil
Ricirus oil
Tangantangan oil

Skin and Eye Irritation and References

Route/Organism	Dose	Effect	Reference
eye /rabbit	500 mg	mild	AJOPAA 29,1363,1946
skin /guinea pig	100 mg/24H	mild	CTOIDG 94(8),41,1979
skin /man	50 mg/48H	mild	CTOIDG 94(8),41,1979
skin /rabbit	100 mg/24H	severe	CTOIDG 94(8),41,1979
skin /rat	100 mg/24H	mild	CTOIDG 94(8),41,1979

Reproductive Effects Data and References

Route/Organism	Dose	Effect	Reference
intramuscular/rat	1 mL/kg (1D prior to copulation)	Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)	EKFAE9 57,49,1994

Acute Toxicity Data and References

Route/Organism	Dose	Effect	Reference
intramuscular/rat	lowest published toxic dose: 1 mL/kg	Endocrine: Effect on menstrual cycle Reproductive: Maternal effects: Oogenesis Reproductive: Maternal effects: Uterus, cervix, vagina	EKFAE9 57,49,1994
oral/mouse	lowest published toxic dose: 4 mL/kg	Gastrointestinal: Hypermotility, diarrhea	PYTOEY 12,670,2005
oral/rat	lowest published toxic dose: 4 mL/kg	Gastrointestinal: Hypermotility, diarrhea	JOETD7 193,416,2016

Other Multiple Dose Data and References

Route/Organism	Dose	Effect	Reference
oral/rat	lowest published toxic dose: 675 gm/kg/90D- intermittent	Liver: Changes in liver weight	HPV282 -,-,2003

Reviews

Organization	Standard	Reference
TOXICOLOGY REVIEW		FCTOD7 44,1689,2006
TOXICOLOGY REVIEW		PYTOEY 9,352,2002
TOXICOLOGY REVIEW		BPRCG* 21,849,2007

Standards and Regulations

Organization	Standard	Reference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES	Active registration	RBREV* -,358,1998

NIOSH Documentation and Surveillance

Organization	Standard	Reference
National Occupational Exposure Survey 1983	Hazard Code M1030; Number of Industries 195; Total Number of Facilities 32342; Number of Occupations 136; Total Number of Employees Exposed 444011; Total Number of Female Employees Exposed 172359
National Occupational Hazard Survey 1974	Hazard Code M1030; Number of Industries 259; Total Number of Facilities 34810; Number of Occupations 134; Total Number of Employees Exposed 487959

Status in Federal Agencies

Organization	Reference
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP Toxicity studies, RPT# TOX-12, October 2000

Page last reviewed: November 16, 2018

Content source: National Institute for Occupational Safety and Health