Alaska Invasive Bacterial Disease Surveillance Report Haemophilus influenzae – 2015

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Background

AIP has conducted statewide surveillance of invasive Haemophilus influenzae since 1980.  Invasive H. influenzae is a reportable condition to the State of Alaska Division of Public Health (DPH).  Reports of cases of disease caused by this organism are shared between AIP and DPH.

Population

The population of the State of Alaska in 2015 was 737,625; 144,274 (19%) were Alaska Native people.  Source:  AK Dept. of Labor & Workforce Development population estimates.

Case Definition

An isolate of Haemophilus influenzae from a normally sterile site that has been taken from a resident of Alaska.

Methods

Participating laboratories send isolates recovered from sterile sites to the AIP laboratory in Anchorage; materials and forms for isolate shipment and data collection are provided to each laboratory by AIP.  Demographic and clinical information on the cases are collected from a review of medical records.  Annually, AIP asks that each laboratory review their records and provide information on any cases that may have been overlooked.

Invasive Haemophilus influenzae Cases by Race
– Alaska, 2015

Race Cases
n (%)
Age Adjusted Rate* % Male Deaths
n (%)
Alaska Native 10 (45) 6.2 70% 0 (0)
Non-Native 12 (55) 1.7 25% 0 (0)
Total 22 45% 0 (0)

*Cases per 100,000 per percent distribution of Alaska 2010 population

Invasive Haemophilus influenzae, Cases & Rates by Age Group & Race – Alaska, 2015

Alaska Native Non-Native
Age (years) No. Cases Rate* No. Cases Rate*
<2 4 71.9 0 0
2-4 3 32.6 0 0
5-18 0 0 1 0.9
19-54 2 3 3 1
55-64 1 7.3 2 2.4
65+ 0 0 6 9.3
Total 10 6.9 12 2

*Cases per 100,000 population

Invasive Haemophilus influenzae, Clinical Presentations – Alaska, 2015

No. %*
Pneumonia with bacteremia 12 55
Bacteremia 2 9
Meningitis 2 9
Septic arthritis 2 9
Other 4 20

*Percent of cases

Serotypes of Invasive Haemophilus influenzae Cases by Race & Age Group – Alaska, 2015

Race Age (yrs) a b f NT*
AK Native <2 3 0 0 1
2-18 2 1 0 0
19-64 1 0 0 2
65+ 0 0 0 0
Non-Native <2 0 0 0 0
2-18 0 0 0 1
19-64 0 0 0 4
65+ 0 0 0 5

*Non-typeable

Vaccine Preventable Disease

In recent years, the prevalence of H. influenzae type b (Hib) has declined due to use of a childhood vaccine against this serotype. There was one case of Hib in a child less than 5 years old in 2015; the child was fully vaccinated.